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Lecture 29 - Preparing Single Enantiomers and the Mechanism of Optical Rotation

Lecture 29 - Preparing Single Enantiomers and the Mechanism of Optical Rotation

This video was recorded at CHEM 125 - Freshman Organic Chemistry. Within a lecture on biological resolution, the synthesis of single enantiomers, and the naming and 3D visualization of omeprazole, Professor Laurence Barron of the University of Glasgow delivers a guest lecture on the subject of how chiral molecules rotate polarized light. Mixing wave functions by coordinated application of light's perpendicular electric and magnetic fields shifts electrons along a helix that can be right- or left-handed, but so many mixings are involved, and their magnitudes are so subtle, that predicting net optical rotation in practical cases is rarely simple. Problem sets/Reading assignment: Reading assignments, problem sets, PowerPoint presentations, and other resources for this lecture can be accessed from Professor McBride's on-campus course website, which was developed for his Fall 2008 students. Please see Resources section below. Resources: Professor McBride's web resources for CHEM 125 (Fall 2008)

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